Thursday will mark the 55th anniversary of the day the Moors murderers were found guilty.
On May 6 1966, Ian Brady and Myra Hindley were both sentenced to life imprisonment for their depraved crimes that saw five children murdered in and around Manchester.
The UK case attracted worldwide attention, due in part to the twisted romance between Brady and Hindley.
But they're far from the only killer couple whose murderous impulses seem to have only been enflamed by their burning passion for each other.
Here are six of the deadliest couples of all time, whose twisted romances ended with either prison or death.
Ian Brady and Myra Hindley
The UK's deadliest couple met when 18-year-old Hindley got a job as a typist at Millwards, the chemical distribution company where Brady, 22, was employed.
She became infatuated with him and the two began a relationship that quickly turned toxic.
Obsessed with Nazis, Hindley dyed her hair platinum blonde to look more Aryan. The pair plotted bank robberies and took erotic photos of each other, but it wasn't until 1963 that they began to talk about murder.
They killed their first victim, Pauline Reade, in July after Hindley persuaded the 16-year-old to help look for her glove in her car. She drove the teen to Saddleworth Moor where Brady sexually assaulted her and cut her throat.
Troubled daughter of evil serial killer considered suicide so she would 'hurt anybody'
Her body was buried on the moor and wasn't found until 1987. The couple went on to kill John Kilbride, 12, Keith Bennett, 12, Lesley Ann Downey, 10, and Edward Evans, 17.
Brady, who died in prison in 2017, once told a journalist that he and Hindley became bored with murder and plotted more ways they could cause torment, once contemplating starting a "small race war" in Manchester.
They were arrested in October 1965 and charged with the murders of Evans, Downey and Kilbride. The following year Brady was found guilty of all three and Hindley for two.
Brady was taken to HM Prison Durham and Hindley to HM Prison Holloway, where she died in 2002.
Paul Bernardo and Karla Homolka
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Paul Bernardo, 23, was already a serial rapist when he met Karla Homolka, 17, in Toronto in the mid-1980s.
Twisted Bernardo was dismayed to discover his girlfriend wasn't a virgin, so Homolka offered up her 15-year-old sister Tammy's virginity instead.
The depraved couple, later known as the "Ken and Barbie killers", tied her up and filmed themselves abusing her for hours before Tammy choked on her own vomit and died.
It was their first kill as a couple, but wouldn't be their last. They went on to murder Leslie Mahaffy, 14, and Kristen French, 15, both schoolgirls who suffered similar ordeals to Tammy.
Meanwhile Bernardo continued to rape women alone and his DNA finally ended up in the police's hands. After he beat Homolka she struck a plea deal with the authorities, exchanging testimony for a lighter sentence.
Paul was sentenced to life in prison and his parole request was denied in 2018, while Homolka served 12 years and was released in 2007 and is now a mum of three.
Fred and Rose West
The Wests are among Britain's most notorious criminals for the murders of 12 young women, including Rose's stepdaughter Charmaine, eight, and daughter Heather, 16.
They hid their victims' bodies at their family home in Gloucester, dubbed the House of Horrors, which was ripped down after the couple were arrested in 1994.
Fred confessed to the killings but Rose has always denied them. She was sent to prison for life for her involvement in 10 of the murders, while Fred took his own life in jail.
Rose's lawyer claims she had a brief "lesbian fling" with the late Myra Hindley while the two served time together.
Bonnie and Clyde
This couple has become synonymous with 1930s gangster glamour, but their real lives were anything but glamorous.
Bonnie Parker was 19 and married to a man in jail for murder when she met Clyde Champion Barrow, 21, in Texas in 1930. He was soon behind bars for a burglary but escaped using a gun Bonnie had smuggled in to him.
He was caught, sent back to jail and paroled in 1932, at which point he and Bonnie began their short-lived life of crime together.
They pulled off a series of robberies that often turned fatal, earning the attention of the FBI. Together they're believed to have murdered at least nine police officers and four civilians
They famously died together in a hailstorm of bullets in 1934.
David and Catherine Birnie
Not widely known outside Australia, this twisted couple stalked the suburbs of Perth in a crazed killing spree over several months in 1986.
Catherine Birnie was a married mum of six when she left her family for David. The two had an intense sex life with David demanding it up to six times a day, sometimes injecting his penis with anaesthetic to enhance his performance.
In the latter half of 1986 they began the murders, driving around the city until they spotted a woman on her own. Catherine would lure her into their car and drive her to their home where she would be chained to the bed.
David Birnie would proceed to rape, torture and kill the victim while Catherine cheered him on, often filming or photographing the horrifying acts.
Four young women died before the Birnies were arrested after one victim managed to escape.
They were both given life sentences. David killed himself in his cell in 2005 (he'd been due to appear in court for the rape of another inmate) while Catherine is only the second Australian woman to ever be permanently denied parole.
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