Can I drink alcohol on penicillin and other antibiotics, what are the risks and how long after taking medication is safe?

IT'S a bummer if you're prescribed antibiotics when you have a big night out on the cards.

Many people would have been warned by their doctor that drinking alcohol while on the medication could be risky.

But is it really true that you shouldn't drink alcohol while on a course of the commonly used drug?

Around two thirds of adults in the UK say they drink on a regular basis.

So if you're one of those, it's handy to know the details of when you can and can't get boozy while on antibiotics:

Can you drink alcohol on antibiotics?

The NHS reassuringly says "it's unlikely that drinking alcohol in moderation will cause problems if you're taking the most common antibiotics" – with some exceptions.

But it says overall, it's a "good idea to avoid drinking alcohol when taking medicine or feeling unwell".

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Some experts say that booze can prevent antibiotics from work properly.

The Mayo Clinic says that alcohol can reduce your energy and delay how quickly you recover from illness.

Alcohol is also a diuretic, causing dehydration, which is never ideal when you are unwell.

Booze can also intesify symptoms of sickness you already have, such as dizziness or drowsiness.

Some antibiotics like linezolid (Zyvox) interact with certain beverages, including red wine and tap beer, causing a dangerous increase in blood pressure.

It's therefore important to read the information leaflet of any antibiotic you have been prescribed if you plan to drink.

Are there any exceptions?

There are some circumstances where people should avoid alcohol altogether, including anyone taking either metronidazole or tinidazole.

Both may be used to clear dental and vaginal infections, or infected leg ulcers and pressure sores, while the latter is sometimes used to help clear bacteria called Helicobacter pylori (H. pylori) from the gut.

Alcohol can cause a serious reaction when combined with these medications. Symptoms can include:

  • Breathlessness
  • Headaches
  • Chest pain
  • Skin flushing
  • Increased or irregular heartbeat
  • Lightheadedness
  • Nausea and vomiting

The NHS says because of the risk, you should avoid drinking for 48 hours after you stop taking metronidazole and 72 hours after you stop taking tinidazole.

There are some antibiotics that can sometimes interact with booze, so you should also be wary of drinking if you are taking:

  • Co-trimoxazole – drinking alcohol while taking co-trimoxazole can occasionally cause a similar reaction to that of metronidazole or tinidazole, although this is very rare.
  • Linezolid – linezolid (mentioned above) can interact with undistilled (fermented) alcoholic drinks, such as wine, beer, sherry and lager.
  • Doxycycline – this is known to interact with alcohol, and the effectiveness of doxycycline may be reduced in people with a history of chronic alcohol consumption.
  • Erythromycin – there is some evidence of a minor interaction with alcohol, which may slightly reduce or delay the effect of erythromycin.

How long after taking antibiotics is it safe to drink?

Some packets of antibiotics specify a time-frame where you should avoid drinking.

For example you should avoid drinking alcohol for at least 24 hours after finishing a prescribed course of metronidazole, and at least 72 hours after finishing a prescribed course of tinidazole.

With other antibiotics, there usually isn’t any adverse side-effect if you drink but it makes sense to avoid alcohol until you have recovered.

What are antibiotics?

Antibiotics are used to treat or prevent certain bacterial infections by killing certain bacteria.

Some antibiotics are also handed out if an infection carries a risk of more serious complications – such as after surgery.

Different antibiotics target different strains of bacteria.

Some are highly specialised and are only effective against particular bacteria while others, called "broad-spectrum" antibiotics, attack a wider range of bacteria.

Doses are either oral, topical – such as creams and lotions used to treat skin infections – or intravenous, meaning they are administered by injection or drip.

The latter tend to be used when an infection is more serious.

What is antibiotic resistance?

The NHS and health organisations across the world are trying to reduce the use of antibiotics because overuse has caused the medicines to become less effective – and led to the emergence of "superbugs".

Superbugs can be serious and challenging to treat, and are becoming an increasing cause of death across the world.

It previously emerged that doctors' warnings that a course of antibiotics must be completed are wrong – and may be putting patients at risk and fuelling the rise of deadly superbugs.

Current NHS advice states “it is essential to finish taking a prescribed course of antibiotics, even if you feel better”.

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