Never miss a drop! Scientists develop new toothpaste container coating that ensures every last morsel of paste comes out of the tube

  • Massachusetts firm’s non-stick coating can be applied to the inside of packaging
  • This means products like sauce and toothpaste effortlessly flow out of the bottle
  • European consumers can try the new coating out with Colgate’s new Elixir line

Squeezing a plastic tube to coax out the last of the toothpaste soon be a distant memory, thanks to new technology developed in the US. 

LiquiGlide, a chemical manufacturing company based in Cambridge, Massachusetts, has partnered with Colgate to roll out its easy-flowing toothpaste solution. 

It’s a non-toxic, non-stick coating that can be applied to the inside of packaging to eliminate the friction between solids and liquids.

This means toothpaste will effortlessly slide out, rather than having to be painfully prised out from every last nook and cranny of the tube. 

European consumers can now try the coating out with Colgate’s new Elixir line, developed in partnership with LiquiGlide.

Elixir comes in a clear, recyclable plastic toothpaste package that allows toothpaste to dispense much more easily.   

Colgate has just introduced a clear, recyclable plastic toothpaste package, developed in partnership with LiquiGlide, that allows toothpaste to dispense much more easily (right)


LiquiGlide is a Cambridge, Massachusetts company founded in 2012 by MIT’s Kripa Varanasi and David Smith. 

The firm manufactures a non-toxic lubricant of the same name.  

The liquid-impregnated coating acts as a slippery barrier between a surface and a viscous liquid. 

Applied inside a condiment bottle, for instance, the coating clings to its sides, while allowing the condiment to glide off completely, with no residue. 

The firm can also design the coatings to be made entirely of food so it’s edible and safe for consumer packaging of food-based products. 

As well as partnerships with Colgate and cosmetics firm Mibelle Group, LiquiGlide has announced its latest $13.5 million funding round, bringing its total amount raised to $50 million to roll out its technology.

Tests so far have been promising – Mibelle Group has reduced the yield loss in its toothpaste manufacturing tanks up to 99 per cent, LiquiGlide claims. 

‘Our technology has redefined what’s possible when working with thick, slow-moving liquids,’ said Dave Smith, co-founder and CEO at LiquiGlide. 

‘We’re already seeing its impact with extraordinary breakthroughs in packaging, manufacturing, and the biomedical industry. 

‘As we continue to expand our market presence with our latest partnerships with Colgate and the Mibelle Group, we’re proud to join forces with global leaders in innovation and consumer goods.’ 

LiquiGlide has already impressed consumer packaging companies with its video demonstration of ketchup effortlessly slipping out of a glass bottle, and has partnered with some European sauce sellers. 

The firm calls its product ‘the first and only permanently wet, slippery surface technology’. 

It’s effectively a super-hydrophobic coating – in other words, a thin surface layer that repels water, much like a lotus leaf. 

A lotus leaf is highly hydrophobic and doesn’t absorb water, meaning water droplets move around its surface without making it wet.  

The surface of a lotus leaf creates a cushion of air for water to sit on, but LiquiGlide replaces this ‘cushion of air’ with a layer of liquid.

This so-called ‘liquid-impregnated surface’ is a multi-layer surface consisting of a customised porous solid and a liquid.

The solid surface is made up of spaces that are sufficiently close to each other to contain the impregnating liquid, and the liquid is held in place to create the permanently slippery surface.

As a result, toothpaste, ketchup, detergent or other product slides on the liquid layer, in a so-called ‘liquid-to-liquid interface’.

And by changing the material used, and the structure of the coating, the researchers can also control the the speed at which liquids slide over the surface. 

For toothpaste, a special toothpaste nozzle makes sure it doesn’t just flow out when the tube lid is opened. 

Pictured, a droplet of water on a lotus leaf, which has provided the inspiration for the LiquiGlide coating

LiquiGlide can be used on both plastic and glass containers and can be adapted for different applications.

This will ultimately help prevent product waste, as any residue that ends up in the packaging that’s too hard for the consumer to extract can end up in the bin. 

Each year, an estimated one million tonnes of condiments are thrown away globally because leftovers cannot be scraped from jars and bottles – and up to 15 per cent of a product remains in its container. 

‘Until now, we’ve accepted significant waste, whether in manufacturing or in packaging, as part of the price for these products because they stick to containers or devices they touch,’ said Professor Kripa Varanasi, co-founder and chairman of LiquiGlide. 

‘By eliminating friction, LiquiGlide’s technology removes this basic constraint. 

‘Now, we can dispense every last drop, minimise yield loss in manufacturing, and reduce occlusions and infections in medical devices.’ 

MailOnline has contacted Colgate regarding its use of plastics in relation to the plastic waste crisis – and whether it plans to use LiquiGlide with any other types of materials. 


Everyone has their own method of teasing the last dollop from the ketchup bottle.

It usually involves much shaking and thumping or perhaps a karate chop at a specific spot on the neck of the bottle.

But help is at hand. Some of the world’s best scientific minds have been working for a decade to find an easier way to overcome a vexing challenge that has been confounding us for generations.

LiquiGlide has been creating and studying slippery surfaces for use in industrial equipment such as steam turbines and desalination plants.

And the firm used its findings to make internal non-stick coatings for containers of all kinds so the contents will flow out smoothly – right down to the last drop. 

Their coating, also called LiquiGlide, acts as a slippery barrier between a surface and a viscous liquid.

Applied inside a condiment bottle, the coating clings permanently to its sides, while allowing the food to glide off without leaving a residue.

According to its inventors, millions of tons of products including sauces and toothpaste are thrown away globally every year because leftovers cannot be scraped from jars and bottles.

In 2015, Norwegian consumer-goods producer Orkla has signed a licensing agreement to use the LiquiGlide’s coating for mayonnaise products sold in Germany, Scandinavia, and several other European nations. 

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